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Innovative therapies to manage eosinophilic esophagitis

Innovative therapies to manage eosinophilic esophagitis

Eosinophilic esophagitis, or (EoE) is a rare, chronic allergic condition affecting the esophagus. In this, several white blood cells, known as eosinophils, are found in the inner lining of the esophagus, where typically there are none. These cells release inflammatory substances, resulting in symptoms such as difficulty in swallowing dry or dense solid foods and loss of appetite. Although EoE is not curable, these innovative eosinophilic esophagitis treatments have been developed to manage the symptoms.

Prescriptions
This treatment involves the use of prescription-based antibodies, which are administered intravenously. This helps in lowering the inflammation caused by EoE. Furthermore, it improves the ability to swallow foods. This eosinophilic esophagitis treatment is usually used to treat persons above the age of 12 years or older.

Dilation
As EoE progresses, it causes the esophagus to become narrower. Over time, severe narrowing makes it difficult to swallow liquids as well. This is also referred to as stricture. In such cases, a person with EoE undergoes the process of dilation.
In this procedure, a balloon is passed to the esophagus via an endoscopy. It is inflated in the area of the esophagus where the narrowing is severe. The inflation is large enough to stretch the esophagus just a bit without rupturing it. This process helps in alleviating some of the symptoms of EoE. It makes it easier to swallow. However, it does not alleviate the underlying inflammation.

Empiric elimination meal plans
One of the well-known ways to treat EoE is by eliminating food allergens, which can trigger and aggravate inflammation. Some of the common food groups that are usually removed from daily meals include the following.

Dairy products
Wheat-based foods
Egg and egg-based food products
Soy-based foods

These foods are slowly added back to meals over time. However, follow-up endoscopies are done after the addition of each food group. This helps in determining which types of food are triggering EoE symptoms. Alternatively, only one of these food groups is eliminated from meals at a time. This is followed by an endoscopy. Depending on the results of the test, that particular food group would be added back or removed from meal plans. Then, the same process is followed for the next food group. This treatment has been found to be quite effective, but it is tedious and difficult to follow. Therefore, it must be done under the supervision of a professional doctor and nutritionist.

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Joint conditions – Symptoms, causes, and risks

Joint conditions – Symptoms, causes, and risks

Joint conditions refer to any condition or disease that affects the joints. Arthritis is the most well-known and commonly occurring joint disease, while there are several others that impact the health of individuals across the world. Diseases related to the joints can be both short-lived or they can turn chronic and require surgery and other serious treatment. This condition can be limited to a single joint or it can impact different parts of the body. There are two types in which joint conditions can be classified: inflammatory and non-inflammatory. However, one thing that is common with most joint conditions is that they’re very painful, especially inflammatory diseases. Symptoms of joint conditions There are several symptoms of joint conditions. While most of them will involve pain, some of them might just involve a difference in shape or a bulge around the joint. This will be the earlier stage of any joint condition, and if a person visits a doctor during this stage, treatment can be fairly simple. Let us understand the different symptoms of joint conditions: The area surrounding the joint is swollen or there is prominent redness in the area. If you touch it, and the area is warm, you might want to consult the doctor.

All you need to know about kidney and liver failure

Hepatorenal syndrome is a condition that is identified as a type of kidney failure that occurs in people who have serious damage caused to the liver, commonly due to cirrhosis. When the kidney stops functioning, toxins begin to accumulate in the body which leads to liver failure as well. Therefore, kidney and liver failures are co-dependent in this case. This condition is of two types: 1 and 2. In Type 1 the kidney failure is more rapid, while type 2 patients tend to move gradually toward renal failure and the symptoms are less aggressive. Symptoms The symptoms caused by the hepatorenal syndrome are a cause of medical emergency in most cases. If any of the symptoms associated with the condition occur, the patient must be rushed to a doctor without any delay. The common symptoms associated with the condition include Nausea Increase in body weight Confusion Reduced urination Change in the color of urine, which usually becomes dark-colored Swelling in the abdomen area Jaundice Dementia Vomiting Delirium Causes and risk factors In most cases, the hepatorenal syndrome is a complication associated with liver disease. Almost in all patients, the condition is caused as a result of liver cirrhosis. When a person suffers from cirrhosis of the liver, there are several factors that can cause the hepatorenal syndrome, such as Infections, especially the ones that affect the kidneys Digestive tract disorders such as gastrointestinal bleeding Use of diuretics, the substance used for increased production of urine The primary reason behind the condition is mostly any kind of disease related to the liver.

Menopause – Symptoms, causes, and risks

Menopause is a stage that marks the end of a woman’s menstrual cycles and fertility, and it is diagnosed when a woman doesn’t menstruate for 12 consecutive months. Usually, menopause occurs in women between the ages of 40s and 50s, but in some cases, early onset may cause a woman to reach menopause in her late 30s as well. Menopause can lead to the development of several symptoms and can cause a lot of discomfort, but no medical attention is required in most cases. This article outlines what you need to know about menopause. Symptoms of menopause The time that leads up to menopause is also known as perimenopause, and it can be accompanied by various symptoms, including the following: Irregularities in the menstrual cycle Vaginal dryness Hot flashes and night sweats Cold chills Sleep-related problems Mood swings Increase in body weight Reduced metabolism Hair thinning Skin dryness Reduced breast fullness The symptoms caused by menopause, including the irregularities in the menstrual cycle, can vary from one woman to another. During perimenopause, it is common as well as expected for a woman’s menstrual cycles to be irregular or skipped. Some women do not get their cycles for several months, followed by normal cycles for a few months.

Symptoms, causes, and risk factors of mental health issues

Mental health is a term that is collectively used to understand illnesses that include symptoms that might have an impact on the thinking, mood, and behavior of a person. Mental health problems might make it difficult for people to concentrate on work or maintain a positive work-life balance. There might even be problems pertaining to relationships when a person is dealing with mental health problems. While mental health and stress have a complex but definite relationship, the latter can gravely be worsened by the former. What is the solution? While some people resort to counseling for mental health problems, some might turn to medication. A combination of both can also be a good and effective solution for some. Symptoms of mental health problems The symptoms of mental health illness can vary depending on the individual, the depth of the problem, and how a person is looking to cope with the problem. There can be emotional and behavioral repercussions of mental health illness, and the best way to cure is to identify it early on and support the person suffering from mental health issues as well as possible. Some of the known symptoms of mental health illnesses include: Feeling sad or low Inability to concentrate on the job or even on leisure activities like watching TV or reading the newspaper Extreme feeling of guilt Irrational fears or worries, especially about the future Mood swings Withdrawal from family, friends, and all sorts of social activities Detachment from the real world and a sense of delusion or hallucinations Inability to keep up with daily tasks or powerlessness in handling the stress of simple jobs Difficulty in understanding people and situations Excessive alcohol use Sudden change in eating habits Change in sex drive for the worse Change in temperament and sudden hostile behavior and loss of patience Suicidal thoughts Physical symptoms such as stomach ache, back pain, and headaches Causes of mental health problems Multiple causes can be associated with the occurrence of mental health illnesses.

Oral health issues – Causes and tips to prevent them

Although maintaining oral hygiene is important for overall health, several mouth and teeth diseases can make it difficult to have the pearly whites you desire. This makes it important to be careful about oral hygiene and make regular efforts to maintain oral health. This article discusses the symptoms and causes of mouth and teeth diseases, followed by a few tips to maintain good oral hygiene. Symptoms Several mouth and teeth problems can be caused by oral health issues. Here are some symptoms that you need to keep in mind to help prevent oral diseases: Foul breath Bleeding gums Loosening of teeth Aches in the tooth, jaw, or gum These are the most common symptoms that are often overlooked, but ignoring them can worsen the pain and aggravate mouth and teeth problems. It’s best to consult a dentist at the earliest if any of these symptoms manifest. Causes The causes of mouth and teeth problems may vary from person to person, but let’s look at the most common causes: Smoking Smoking causes several health issues, and mouth and teeth problems are just one among those. It harms the tissues of the gums and the nicotine also stains the teeth. Poor dental history in the family If your family has a poor dental record, you should take extra precautions to maintain oral health as you face a greater risk of developing mouth and teeth problems.